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    • Home
    • About Us
      • What is Harm Reduction?
      • Meet the Team
      • Mission, Vision, & Values
      • Contact Us
    • Research Projects
      • Drug Checking
      • OD Detection Technologies
      • Sleep and MOUD
      • Completed Projects
    • Publications and Posters
      • Publications
      • Research Posters
      • Select Presentations
    • Resources
      • Infographics
      • Additional Websites
    • Español
      • Inicio
      • Reducción de Danos
      • Conoce al Equipo
      • Misión, Visión & Valores
      • Trabajos de Investigación
      • Publicaciones y Posteres
      • Recursos
Harm Reduction Innovation Lab

401-212-4730

  • Home
  • About Us
    • What is Harm Reduction?
    • Meet the Team
    • Mission, Vision, & Values
    • Contact Us
  • Research Projects
    • Drug Checking
    • OD Detection Technologies
    • Sleep and MOUD
    • Completed Projects
  • Publications and Posters
    • Publications
    • Research Posters
    • Select Presentations
  • Resources
    • Infographics
    • Additional Websites
  • Español
    • Inicio
    • Reducción de Danos
    • Conoce al Equipo
    • Misión, Visión & Valores
    • Trabajos de Investigación
    • Publicaciones y Posteres
    • Recursos

Naloxone Programs

High-dose naloxone formulations project

Naloxone is an FDA-approved opioid antagonist medication for reversing opioid overdoses. Naloxone is available to the public, and can be administered through intramuscular (IM), intravenous (IV), and intranasal spray (IN) routes. 


This literature review, being conducted in collaboration with Tennessee Harm Reduction, aims to improve understanding regarding the adequacy of two doses of low-dose IM or IN naloxone in effectively reversing fentanyl overdoses in community settings and whether high-dose naloxone formulations (HDNF) are an optimal or necessary solution to the fentanyl epidemic. We will incorporate the perspectives and experiences of people who use drugs, enabling a more practical and contextually-grounded analysis than what is currently available on this topic.


Study Status

Completed and published


High-Dose Naloxone Formulations Are Not as Essential as We Thought
Disruptions to naloxone training among lay and occupational responders in Maryland during the emergence of COVID-19
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Harm Reduction Innovation Lab

1125 North Main Street, Providence, Rhode Island 02904, United States

401-212-4730

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